Alcohols and polyols
- (1)
- (55)
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- (39)
- (4)
- (8)
- (7)
- (55)
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- (7)
- (18)
- (1)
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- (153)
- (1)
- (65)
- (27)
- (14)
- (3)
- (1)
- (1)
- (10)
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- (2)
- (2)
- (1)
- (1)
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- (1)
- (1)
- (1)
- (6)
- (2)
- (30)
- (4)
- (20)
- (10)
- (2)
- (10)
- (4)
- (5)
- (395)
- (6)
- (102)
- (21)
- (50)
- (31)
- (61)
- (13)
- (14)
- (1)
- (2)
- (1)
- (26)
- (6)
- (4)
- (1)
- (6)
- (1)
- (462)
- (9)
- (46)
- (11)
- (45)
- (6)
- (1)
- (7)
- (10)
- (145)
- (114)
- (6)
- (5)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (4)
- (7)
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- (1)
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- (1)
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- (2)
- (2)
- (2)
- (16)
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- (30)
- (2)
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- (1)
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- (20)
- (10)
- (4)
- (15)
- (1)
- (4)
- (6)
- (2)
- (2)
- (2)
- (2)
- (4)
- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
- (5)
- (4)
- (17)
- (15)
- (4)
- (5)
- (2)
- (5)
- (4)
- (33)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (8)
- (7)
- (7)
- (2)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (3)
- (1)
- (15)
- (12)
- (1)
- (2)
- (2)
- (7)
- (12)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (17)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (7)
- (4)
- (1)
- (1)
- (3)
- (6)
- (11)
- (5)
- (3)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (2)
- (1)
- (3)
- (2)
- (10)
- (1)
- (2)
- (4)
- (4)
- (3)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (5)
- (4)
- (1)
- (2)
- (9)
- (4)
- (2)
- (12)
- (4)
- (1)
- (1)
- (5)
- (3)
- (10)
- (2)
- (5)
- (1)
- (1)
- (1)
- (10)
- (5)
- (1)
- (2)
- (2)
- (6)
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- (1)
- (2)
- (1)
- (1)
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- (1)
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- (1)
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- (1)
- (2)
- (2)
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- (1)
- (1)
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- (1)
- (1)
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- (1)
- (1)
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- (1)
- (1)
- (1)
- (2)
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- (11)
- (1)
- (2)
- (4)
- (20)
- (21)
- (1)
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- (8)
- (2)
- (3)
- (3)
- (8)
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- (2)
- (1)
- (1)
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- (1)
- (2)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
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- (12)
- (9)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
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- (1)
- (1)
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- (1)
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- (60)
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- (2)
- (1)
- (1)
- (30)
- (2)
- (2)
- (11)
- (82)
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- (1)
- (3)
- (7)
- (5)
- (1)
- (81)
- (3)
- (378)
- (4)
- (40)
- (21)
- (1)
- (19)
- (1)
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- (1)
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- (2)
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Selleck Chemical LLC INCB3344-5mg
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INCB3344 is a potent, selective and orally bioavailable CCR2 antagonist with IC50 values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity.
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eMolecules Medchem Express / Ginsenoside Rk1 / 5mg / 552386880 / HY-N2515 / / 494753-69-4 / MFCD28124355 / 767.010 / C42H70O12
Medchem Express / Ginsenoside Rk1 / 5mg / 552386880 / HY-N2515 / / 494753-69-4 / MFCD28124355 / 767.010 / C42H70O12
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Ambeed CONDURITOL B EPOXIDE-100MG
Conduritol B Epoxide, 100MG, CAS# 6090-95-5, MW: 162.14
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![eMolecules Medchem Express / Vinorelbine (ditartrate) / 10mg / 446260642 / HY-12053A / / 125317-39-7 / [null] / 1079.119 / C53H66N4O20](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502446288.PNG-250.jpg)
eMolecules Medchem Express / Vinorelbine (ditartrate) / 10mg / 446260642 / HY-12053A / / 125317-39-7 / [null] / 1079.119 / C53H66N4O20
Medchem Express / Vinorelbine (ditartrate) / 10mg / 446260642 / HY-12053A / / 125317-39-7 / [null] / 1079.119 / C53H66N4O20
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Medchemexpress LLC HY-B0011 200mg , Docetaxel CAS:114977-28-5 Purity:98%
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Medchemexpress, HY-B0011 200mg Docetaxel CAS:114977-28-5 Formula:C43H53NO14 Microtubule Purity:98% Docetaxel is a semi-synthetic taxane analogue, acts as a microtubule stabilizer. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Selleck Chemical LLC Vinblastine sulfate S4505-100mg
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Vinblastine sulfate inhibits microtubule formation and suppresses nAChR activity with IC50 of 8 9 M in a cell-free assay used to treat certain kinds of cancer Vinblastine sulfate induces autophagy and apoptosis
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Medchemexpress LLC HY-N0434 5mg Medchemexpress, Astragaloside III CAS:84687-42-3 Purity:>98%
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Medchemexpress, HY-N0434 5mg Astragaloside III CAS:84687-42-3 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-N0267 50mg Medchemexpress, Hypaconitine CAS:6900-87-4 Purity:>98%
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Medchemexpress, HY-N0267 50mg Hypaconitine CAS:6900-87-4 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC SRI-37330 hydrochloride | 2322245-49-6 | 99.7% | C16H20ClF3N4O2S | 1 ML
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SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor. It reduces hepatic glucose production, reverses hepatic steatosis, and inhibits glucagon secretion and function, making it a promising compound for type 2 diabetes research.
- Inhibits thioredoxin-interacting protein (TXNIP)
- Reduces hepatic glucose production
- Reverses hepatic steatosis
- Potential for type 2 diabetes research
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Medchemexpress LLC VU0357017 hydrochloride | 1135242-13-5 | 98.6% | 369.89 | 50 MG
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VU0357017 hydrochloride is a potent, selective, and brain-penetrant allosteric agonist of the M1 muscarinic acetylcholine receptor, exhibiting an EC50 of 477 nM. This compound demonstrates high selectivity for M1, showing no activity at M2-M5 receptors at concentrations up to 30 μM. It is being investigated for its potential use in the research of Alzheimer's disease and schizophrenia.
- Potent and selective allosteric agonist of M1 muscarinic acetylcholine receptor.
- Brain-penetrant.
- Highly selective for M1, with no activity at M2-M5 receptors at tested concentrations.
- Induces calcium release and ERK phosphorylation in CHO cells.
- Reverses scopolamine-induced cognitive deficits in animal models.
- Potential for research in Alzheimer's disease and schizophrenia.
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Medchemexpress LLC CCG258208 hydrochloride | 98.1% | 488.94 | 25 MG
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CCG258208 (GRK2-IN-1) hydrochloride is a potent and selective inhibitor of GRK2 (G protein-coupled receptor kinase 2) with an IC50 of 30 nM. It demonstrates significant selectivity, being 230-fold more selective over GRK5 (IC50=7.09 μM) and over 2500-fold more selective over GRK1 (IC50=87.3 μM), PKA, and ROCK1. This compound is utilized in heart failure research.
- Potent and selective GRK2 inhibitor (IC50=30 nM).
- High selectivity over GRK5 (230-fold).
- Even higher selectivity over GRK1, PKA, and ROCK1 (more than 2500-fold).
- Applicable in heart failure research.
- Shows significant improvement in βAR-stimulated contractility in mouse cardiomyocytes at concentrations as low as 0.1 μM.
- Exhibits a superior half-life *in vivo*.
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Medchemexpress LLC Littorine hydrochloride | 21956-47-8 | >95.0% | 325.83 | C17H24ClNO3 | 5 MG
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Littorine hydrochloride is the hydrochloride salt of littorine, an alkaloid found in Anthocercis fittorea and Datura species. It is supplied as a small-scale research chemical with documented molecular and solubility data for in vitro preparation.
- Hydrochloride salt of littorine, an alkaloid found in plant species.
- Molecular formula C17H24ClNO3; molecular weight 325.83.
- Soluble in DMSO at 50 mg/mL (153.45 mM); may require ultrasonic treatment.
- Available in small research quantities (1 mg, 5 mg, 10 mg).
- Store under conditions recommended in the certificate of analysis.
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Medchemexpress LLC Ponatinib (hydrochloride) | 1114544-31-8 | 99.8% | 569.02 | 10 MG
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Ponatinib hydrochloride is a hydrochloride of ponatinib, an orally active multi-targeted kinase inhibitor. It targets Abl, PDGFRα, VEGFR2, FGFR1, and Src with various IC50s.
- Reduces the viability, migration, and function of human endothelial cells.
- Decreased cell viability in HUVEC cells in a dose-dependent manner.
- Increased the percentage of annexin/PI labeled cells in HUVEC cells.
- Reduced VEGF-induced migration in HUVEC cells.
- Protects mice from lethal influenza infection by inhibiting cytokine storm.
- Treated mice had higher survival rates and reduced the infiltration of neutrophils.
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Medchemexpress LLC Vatinoxan hydrochloride | 130466-38-5 | 99.79% | 454.97 | 25 MG
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Vatinoxan hydrochloride is a peripheral α2 adrenergic receptor antagonist. It has been shown to increase cardiac index and tissue oxygen delivery without deleterious adverse effects when administered alone. Furthermore, it attenuates or prevents dexmedetomidine's systemic hemodynamic effects in a dose-dependent manner and shortens the sedative effect without altering its quality. This product is intended for research use only.
- Peripheral α2 adrenergic receptor antagonist.
- Increases cardiac index and tissue oxygen delivery.
- Attenuates or prevents dexmedetomidine's systemic hemodynamic effects.
- Shortens sedative effect without altering its quality.
- Intended for research use only.
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Medchemexpress LLC SB-612111 hydrochloride | 99.6% | 454.86 | 100 MG
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SB-612111 hydrochloride is a novel and potent opiate receptor-like orphan receptor (ORL-1) antagonist with a high affinity for hORL-1 (Ki=0.33 nM). It exhibits selectivity for μ-, κ- and δ-receptors with Ki values of 57.6 nM, 160.5 nM, and 2109 nM, respectively. SB-612111 hydrochloride effectively antagonizes the pronociceptive action of Nociceptin in an acute pain model.
- Novel and potent ORL-1 antagonist
- High affinity for hORL-1 (Ki=0.33 nM)
- Selectivity for μ-, κ- and δ-receptors
- Effectively antagonizes pronociceptive action of Nociceptin in an acute pain model
- Purity: 99.64%
- Available in solid form (white to off-white)
- In-stock for 100 mg quantity
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